|
1. Accepted major perpetrators |
2. Rejected perpetrators |
3. Unclassifiable |
4. Full table |
capecitabine did not meet the criteria of being an inhibitor or inducer of CYP2C9.
capecitabine
| CYP2C9 | |
|---|---|
| Criteria not met | capecitabine [1] itraconazole [2] |
- Criteria not met: drugs evaluated in clinical PK interactions studies that do not meet the inclusion criteria (see Methods).
Footnotes and References
| 1. | Camidge R, Reigner B, Cassidy J, Grange S, Abt M, Weidekamm E, Jodrell D. Significant effect of capecitabine on the pharmacokinetics and pharmacodynamics of warfarin in patients with cancer. Journal of Clinical Oncology 2005; 23: 4719-25.[PubMed] |
| 2. | Kivisto KT, Kantola T, Neuvonen PJ. Different effects of itraconazole on the pharmacokinetics of fluvastatin and lovastatin. British Journal of Clinical Pharmacology 1998; 46: 49-53.[PubMed] |
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