| 1. Accepted major perpetrators | 2. Rejected perpetrators | 3. Unclassifiable | 4. Full table |
citalopram did not meet the criteria of being an inhibitor or inducer of CYP2D6 and CYP3A.
- Criteria not met: drugs evaluated in clinical PK interactions studies that do not meet the inclusion criteria (see Methods).
Footnotes and References
|a.||clinical PK interaction studies referred to in product information.|
|b.||likely to be a major inhibitor based on subjective evaluation (≥ 2-fold AUC increase or ≥ 50% decrease in clearance of in vivo CYP probe).|
|c.||likely to be a major inducer based on subjective evaluation (≥ 2-fold decrease in AUC or ≥ 50% increase in clearance of in vivo CYP probe).|
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